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ROLE OF THE RED GLAND IN MERCENARIA MERCENARIA IN DETOXIFICATION
Citation:
Zaroogian, G., P. Yevich, AND S. Pavigano. ROLE OF THE RED GLAND IN MERCENARIA MERCENARIA IN DETOXIFICATION. U.S. Environmental Protection Agency, Washington, D.C., EPA/600/J-89/487 (NTIS PB91117515).
Description:
Brown cells of the red gland in Mercenaria mercenaria are involved in the excretory process. e studied their involvement in the removal of foreign substances from the tissues of Mercenaria. Toluidine blue (soluble dye) accumulated in brown cells after dye injection into the foot muscle and after addition to brown cell isolates. n comparison, carmine red (particulate dye) did not accumulate under the same conditions. ITC-labeled bovine albumen accumulated in brown cells when introduced in vivo and to cell isolates. inetic studies indicated up take of FITC-albumen occurred within 2 h when added to cell isolates and within 24 h after injection into the foot muscle. rown cell isolates were separated into three fractioN on a discontinuous Percoll gradient. Fraction I contained primarily what appeared to be precursor brown cells. he majority of the cells infraction 2 were brown cells. raction 3 was entirely brown globular material. ssays indicated the presence of acid phosphatase, glutathione reductase and lysozyme in lysates from each fraction. hus it appears that brown cells of the red gland contain enzymes involved in detoxification and degradative processes.