You are here:
CHAPTER 7: EPIDEMIOLOGY/HUMAN DATA - HEALTH ASSESSMENT FOR 2,3,7,8-TETRACHLORODIBENZO-P-DIOXIN (TCDD) AND RELATED COMPOUNDS
Citation:
Whitlock, Jr., J. CHAPTER 7: EPIDEMIOLOGY/HUMAN DATA - HEALTH ASSESSMENT FOR 2,3,7,8-TETRACHLORODIBENZO-P-DIOXIN (TCDD) AND RELATED COMPOUNDS. U.S. Environmental Protection Agency, Washington, D.C., EPA/600/AP-92/001g.
Description:
The U.S. Environmental Protection Agency (EPA) is conducting a scientific reassessment of the risks of exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and chemically similar compounds collectively known as dioxin. PA has undertaken this task in response to emerging scientific knowledge of the biological, human health, and nvironmental effects of dioxin. ignificant advances have occurred in the scientific understanding of mechanisms of dioxin toxicity, of the carcinogenic and other adverse health effects of dioxin in people, of the pathways to human exposure, and of the toxic effects of dioxin to the environment. his is one of eight draft chapters that will ultimately be part of a full health assessment of TCDD and related compounds. Chapter 7. Epidemiology/Human Data, provides an analysis of the literature on cancer and non-cancer effects. he original research reports are discussed in 4 groups: 1) follow-up studies of chemical manufacturing and processing workers, 2) case-control studies in general populations, 3) studies of pulp and paper mill workers, and 4) other studies (e.g., pesticide applicators, Vietnam veterans potentially exposed to Agent Orange, residents of Seveso, Italy, and victims of contaminated rice oil poisonings).