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EVALUATION OF THE POTENTIAL CARCINOGENICITY OF ACRYLONITRILE
Citation:
EVALUATION OF THE POTENTIAL CARCINOGENICITY OF ACRYLONITRILE. U.S. Environmental Protection Agency, Washington, D.C., EPA/600/8-91/058.
Description:
Acrylonitrile is a probable human carcinogen, classified as weight-of-evidence Group Bl under the EPA Guidelines for Carcinogen Risk Assessment. vidence, on potential carcinogenicity from animal studies is "Sufficient," and the evidence from human studies is @'Limited." he potency factor (F) for acrylonitrile is estimated to be 2.28 (derived from human pidemiology data) (mg/kg/day)-1, placing it in potency group 2 according to the CAG's methodology for evaluating potential carcinogens. ombining the weight-of-evidence group and the potency group, acrylonitrile is assigned a "MEDIUM" hazard ranking for the purposes of RQ adjustment.