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EFFECT OF AGGREGATION ON VIBRIO CHOLERA INACTIVATION
Citation:
Clark, R., E.W. Rice, B. Pierce, C. Johnson, AND K. Fox. EFFECT OF AGGREGATION ON VIBRIO CHOLERA INACTIVATION. U.S. Environmental Protection Agency, Washington, D.C., EPA/600/J-94/364 (NTIS PB94209707).
Description:
Extensive research has shown that microorganisms exhibit increased resistance due to clumping, aggregation, particle association or modification of antecedent growth conditions. uring the course of investigating a major waterborne V. Cholerae outbreak in Peru, U.S. EPA investigators discovered an extremely rough form of V. Cholerae that was highly resistant to disinfection by chlorine. his form of V. Cholerae also tends to form large aggregates, which contribute to the resistance. article counting was used to characterize each of the cultures examined. tatistical analysis revealed that the rugose or rough strain of V. Cholerae was much more resistant to disinfection than the common or smooth strain. esistance was attributed to both aggregation and a mucoid-coating. he larger aggregates associated with the rugose organism are of a size as to be easily removed by filtration, but if the variant were to contaminate a distribution system through a line break or cross connection it would be difficult to control by chlorine disinfection.