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REVIEW OF TERMS FOR REGULATED VERSUS FORCED, NEUROCHEMICAL-INDUCED CHANGES IN BODY TEMPERATURE
Citation:
Gordon, C. REVIEW OF TERMS FOR REGULATED VERSUS FORCED, NEUROCHEMICAL-INDUCED CHANGES IN BODY TEMPERATURE. U.S. Environmental Protection Agency, Washington, D.C., EPA/600/J-82/075 (NTIS PB83213900).
Description:
Deviations of the body temperature of homeothermic animals may be regulated or forced. A regulated change in core temperature is caused by a natural or synthetic compound that displaces the set-point temperature. A forced shift occurs when an excessive environmental or endogenous heat load, or heat sink, exceeds the body's capacity to thermoregulate but does not affect set-point. A fever is the paradigm of a regulated increase in body temperature, but the term fever has acquired a strict pathological definition over the past two decades. Consequently, other forms of nonpathological regulated elevations in body temperature--either forced or regulated vs. a forced temperature change, a confusion of terms has been created in the literature.