You are here:
UNUSUAL EOSINOPHILIC GRANULE CELL PROLIFERATION IN COHO SALMON (ONCHORHYNCHUS KISUTCH)
Citation:
Kent, M., M. Powell, D. Kieser, D. Speare, J. Burka, K. Bagshaw, AND J. Fournie. UNUSUAL EOSINOPHILIC GRANULE CELL PROLIFERATION IN COHO SALMON (ONCHORHYNCHUS KISUTCH). U.S. Environmental Protection Agency, Washington, D.C., EPA/600/J-94/007 (NTIS PB94140738).
Description:
Proliferative lesions comprised of eosinophilic granule cells (EGCs) extended throughout the gastrointestinal tract of several mature, spawning coho salmon Oncorhynchus kisutch (Walbaum). istological examination of the tumour showed extensive proliferation and infiltration of EGCs within the lamina propria, stratum compactum, and serosa of the intestine and pyloric caeca. here was a similar infiltration of replacement of the pancreatic and adipose tissues associated in the pyloric caeca by the proliferating EGCs. ild diffuse infiltration was also observed in the spleen, liver, and kidney of affected fish. istochemical analysis and ultrastructural examination showed that the apparently neoplastic granular cells of the tumour to be essentially identical to the EGCs, which are usually concentrated with the stratum granulosum of the intestine in normal salmonid fishes.
URLs/Downloads:
UNUSUAL EOSINOPHILIC GRANULE CELL PROLIFERATION IN COHO SALMON (ONCHORHYNCHUS KISUTCH)