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EXPOSURE OF HUMANS TO A VOLATILE ORGANIC MIXTURE: I. BEHAVIORAL ASSESSMENT
Citation:
Otto, D., K. Hudnell, D. House, L. Molhave, AND W. Counts. EXPOSURE OF HUMANS TO A VOLATILE ORGANIC MIXTURE: I. BEHAVIORAL ASSESSMENT. U.S. Environmental Protection Agency, Washington, D.C., EPA/600/J-92/195 (NTIS PB92189018), 1992.
Description:
Subjective reactions of discomfort, impaired air quality, irritation of mucosal membranes, and impaired memory have been reported to chemically sensitive subjects during exposure to volatile organic compounds (VOC's) found in new buildings. 6 normal healthy male subjects aged 18-39 were exposed for 2.7 hrs. to a complex VOC mixture at 0 and 25 mq/m3. ach subject completed control and exposure sessions at one week intervals in counterbalanced order. easurements included comfort ratings of eye, nose and throat irritation, symptom questionnaire and computerized behavioral tests. OC exposure did not affect performance on any behavioral tests. Further studies are needed to determine if the performance of chemically sensitive subjects is affected by VOC exposure at this concentration. esults of comfort ratings and sensory irritation will be reported in a comparison paper.