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METHODS FOR ASSESSING RAT SPERM MOTILITY
Citation:
METHODS FOR ASSESSING RAT SPERM MOTILITY. U.S. Environmental Protection Agency, Washington, D.C., EPA/600/J-92/229 (NTIS PB92195825), 1992.
Description:
Computer-assisted sperm analysis (CASA) systems are becoming more widely used. ith this spread of technology come more data from toxicology studies, designed to determine if treatment with putative toxicants affects sperm motion parameters. hile these CASA methods provide us with more ways to evaluate toxicity, and thus perhaps increase our chances of successfully protecting human health, there is also a greater likelihood that different laboratories will use different methods of collecting data on sperm motility. ifferent systems and different methods will produce data that are difficult to compare. n a prospective attempt to address this issue of comparability and limit the problems, a group of individuals using CASA systems to analyze rat sperm motility convened to discuss methodologies issues, share data, and tried to reach a consensus about methods for performing these studies. his manuscript shares those meetings and data in the hope that common methods will enhance inter-laboratory comparisons.