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ADENOCARCINOMA OF THE RETINAL PIGMENT EPITHELIUM IN THE GUPPY POECILIA RETICULATA PETERS
Citation:
Fournie, J., W. Hawkins, AND W. Walker. ADENOCARCINOMA OF THE RETINAL PIGMENT EPITHELIUM IN THE GUPPY POECILIA RETICULATA PETERS. U.S. Environmental Protection Agency, Washington, D.C., EPA/600/J-92/387 (NTIS PB93121192), 1992.
Description:
A single case of adenocarcinoma of the retinal pigment epithelium occurred in a guppy, Poecilia reticulata Peters. his is the first such tumor reported from fishes. he left eye of the affected fish was severely exophthalmic because of a large intraocular tumor mass. he tumor, which displaced normal retina anteriorly, consisted mainly of melanin-containing epithelial cells. eoplastic cells were bilayered and arranged in a tubular pattern. he tumor appeared to be confined to the orbit. lthough the specimen was from a group exposed to a mixture of halogenated organic compounds, we do not consider the lesion to have been chemically induced because of its rare occurrence.