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USER'S GUIDE: CHROMOSOMAL ABERRATION DATA ANALYSIS AND INTERPRETATION SYSTEM
Citation:
Tice, R. AND A. Pellom. USER'S GUIDE: CHROMOSOMAL ABERRATION DATA ANALYSIS AND INTERPRETATION SYSTEM. U.S. Environmental Protection Agency, Washington, D.C., EPA/600/8-90/086 (NTIS PB91140376), 1991.
Description:
This user's manual provides guidance to researchers and the regulatory community for interacting with a data analysis and statistical interpretation system, designated as CA. A is dedicated to the in vivo chromosome aberration assay, a routinely used genetic toxicology assay for chemical compounds which may be of health concern. he objective in developing this system has been to promote consistency and intercomparability of assay test results across laboratories, thus providing researchers and government decision makers with a means to assure comparable analyses of test data. he CA data analysis system has been developed in consultation with a panel of biostatisticians and experts in the field of cytogenetics. oftware for executing CA and two sets of test data, contained on two 5.25 inch floppy disks, accompany the user's guide.
