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DELAYED NEUROPATHY IN ADULT PEKING DUCKS INDUCED BY SOME ORGANOPHOSPHORUS ESTERS
Citation:
Soliman, S. AND J. Farmer. DELAYED NEUROPATHY IN ADULT PEKING DUCKS INDUCED BY SOME ORGANOPHOSPHORUS ESTERS. U.S. Environmental Protection Agency, Washington, D.C., EPA/600/J-84/306 (NTIS PB85214385), 1984.
Description:
Tri-o-cresyl phosphate (TOCP), leptophos (0-methyl 0-(4-bromo-2,5,-dichlorophenyl) phenylphosphonothioate) and cyanofenphos (0-ethyl 0-(4-cyanophenyl) phenylphosphonothioate) were used to determine whether adult peking ducks would exhibit neurotoxicity after exposure to such chemicals. Clinical, histopathological, and specific biochemical tests were used to detect the neurologic dysfunctions that were induced by these neurotoxic agents. Ducks were orally treated with TOCP or leptophos at 100 or 10 mg/kg(d)for 30 d, respectively. Another group of ducks received cyanofenphos at 4 mg/kg(d)for 10 d.