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EVALUATION OF THE POTENTIAL CARCINOGENICITY OF ETHYLENE OXIDE
Citation:
EVALUATION OF THE POTENTIAL CARCINOGENICITY OF ETHYLENE OXIDE. U.S. Environmental Protection Agency, Washington, D.C., EPA/600/8-91/131 (NTIS PB93192375), 1988.
Description:
Ethylene oxide is a probable human carcinogen, classified as weight-of-evidence Group B2 under the EPA Guidelines for Carcinogen Risk Assessment (U.S. EPA, 1986a). vidence on potential carcinogenicity from animal studies is "Sufficient," and the evidence from human studies is "Limited." he potency factor (F) for ethylene oxide is estimated to be 1.34 (mg/kg/day)-1, placing ft in potency group 2 according to the CAG's methodology for evaluating potential carcinogens (U.S. EPA, 1986b). Combining the weight-of-evidence group and the potency group, ethylene oxide is assigned a "MEDIUM" hazard ranking for the purposes of RQ adjustment. (When the weight-of-evidence is expressed as a range, i.e., Bl, the hazard ranking is based on the higher weight-of-evidence group).
