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FIVE-YEAR FOLLOW-UP STUDY OF CHILDREN WITH LOW-TO-MODERATE LEAD ABSORPTION: ELECTROPHYSIOLOGICAL EVALUATION
Citation:
Otto, D., G. Robinson, S. Baumann, S. Schroeder, AND P. Mushak. FIVE-YEAR FOLLOW-UP STUDY OF CHILDREN WITH LOW-TO-MODERATE LEAD ABSORPTION: ELECTROPHYSIOLOGICAL EVALUATION. U.S. Environmental Protection Agency, Washington, D.C., EPA/600/J-85/266 (NTIS PB86158565), 1985.
Description:
Forty-nine children aged 6 to 12 years were evaluated for residual effects of lead exposure using psychometric, electrophysiological, and medical tests five years after initial assessment. The original range of blood lead (PbB) levels was 6-59 micrograms/dl; the current range was 6-30 micrograms/dl. A linear relationship between PbB and slow brain wave voltage during sensory conditioning was observed at initial evaluation (Otto, et al., 1981) and at two-year follow-up (Otto, et al. 1982). No significant relationship between PbB and slow wave voltage during passive conditioning was found at five-year follow-up, although a linear increase in slow wave negativity relative to current PbB level during active conditioning was suggested by exploratory analyses. Another exploratory analysis revealed a significant linear relationship between original PbB level and the latency of waves III and V of the brainstem auditory evoked potential.