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LABORATORY TEST METHOD OF EXPOSURE BY ORAL AND INTRAVENOUS ROUTES OF MICORBIAL PEST CONTROL AGENTS TO NON TARGET AVIAN SPECIES
Citation:
Fairbrother, A. AND P. Bucholz. LABORATORY TEST METHOD OF EXPOSURE BY ORAL AND INTRAVENOUS ROUTES OF MICORBIAL PEST CONTROL AGENTS TO NON TARGET AVIAN SPECIES. U.S. Environmental Protection Agency, Washington, D.C., EPA/600/3-90/002 (NTIS PB90187071), 1990.
Description:
Microbial pest control agents (MPCAs) are microorganisms applied to the environment to control the proliferation and spread of agricultural or silvicultural insect, arthropod. and plant pests. hen used in this manner, the micrporganisms are classified as pesticides and are subject to labeling and safety regulations defined by the Federal Fungicide, Insecticide, and Rodenticide Act (FIFRA). one of these agents have undergone rigorous testing to determine safety to nontarget invertebrate or vertebrate species. principally because standard protocols for such tests were unavailable. e have been working for the past three years to develop and validate such protocols for nontarget avian species. This report discusses only work done to evaluate oral and I.V. routes: the respiratory exposure methods will be discussed in a separate report. xperiments showed that the protocols are suitably designed to demonstrate pathogenicity of a microorganism in the test bird species and illustrated the potential differences in species susceptibility. he interim protocols were revised to reflect the necessary additional information on husbandry of the two species and changes in requirements of endpoints to be measured. evised protocols are included as an appendix in the report.