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EVALUATION OF THE POTENTIAL CARCINOGENICITY OF DAUNOMYCIN
Citation:
EVALUATION OF THE POTENTIAL CARCINOGENICITY OF DAUNOMYCIN. U.S. Environmental Protection Agency, Washington, D.C., EPA/600/8-91/098.
Description:
Daunomycin is a probable human carcinogen, classified as weight-of-evidence Group B2 under the EPA Guidelines for Carcinogen Risk Assessment (U.S. EPA, 1986a). vidence on potential carcinogenicity from animal studies is "Sufficient," and the evidence from human studies is "No Data." ata available are inadequate for calculating a potency factor (F) and no quantitative inferences can be made. aunomycin is, therefore, assigned to the median potency factor range and placed in potency group 2 according to the CAG's methodology for evaluating potential carcinogens (U.S. EPA, 1986b). ombining the weight-of-evidence group and the potency group, daunomycin is assigned a "MEDIUM" hazard ranking for the purposes of RQ adjust.