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OCULAR CHONDROSARCOMAS IN RIVULUS MARMORATUS POEY
Citation:
Courtney, L. AND J. Fournie. OCULAR CHONDROSARCOMAS IN RIVULUS MARMORATUS POEY. U.S. Environmental Protection Agency, Washington, D.C., EPA/600/J-91/101 (NTIS PB91206946).
Description:
Only one documented case of a malignant cartilaginous tumor has been previously reported from fish, a large cranial chondrosarcoma from the paddlefish, Polyodon spathula (Walbaum). escribed here are two chondrosarcomas diagnosed from adult laboratory-reared Rivulus marmoratus Poey, the first reports of this tumor type from an atheriniform fish. istologically, the tumors consisted of cartilage in various stages of differentiation. hese ranged from poorly differentiated areas consisting of a highly cellular, primitive mesenchymal component with numerous mitotic figures and extensive anaplasia to well-differentiated portions expressed as scattered foci of mature cartilage consisting of single and multiple chondrocytes isolated within lacunae. he lesions, possibly arising from the sclera, were invasive into the eye, with elements of the choroid and striated muscle trapped within the tumor matrix. istologically these lesions resemble the paddlefish chondrosarcoma and mesenchymal chondrosarcomas in higher vertebrates.