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FURTHER EVIDENCE THAT DICHLOROMETHANE DOES NOT INDUCE CHROMOSOME DAMAGE
Citation:
Westbrook-Collins, B., Y. Sharief, J. Campbell, AND J.W. Allen. FURTHER EVIDENCE THAT DICHLOROMETHANE DOES NOT INDUCE CHROMOSOME DAMAGE. U.S. Environmental Protection Agency, Washington, D.C., EPA/600/J-90/140 (NTIS PB91109785).
Description:
Dichloromethane (DCM) is a widely used industrial solvent which has been determined to be a carcinogen in rats and mice. n vitro and in vivo analyses of chromosome damage induced by this agent have provided conflicting results. n order to further investigate the clastogenic potential of DCM in vivo, we analyzed SCEs and chromosome aberrations (CAs) in mouse bone marrow cells following intraperitoneal exposures. CM failed to increase the frequencies of either SCEs or CAs.
Record Details:
Record Type:DOCUMENT( REPORT )
Product Published Date:05/24/2002
Record Last Revised:04/16/2004
Record ID:
41194