Science Inventory

CHRYSOTILE ASBESTOS IN KIDNEY CORTEX OF CHRONICALLY GAVAGED RATS

Citation:

Patel-Mandlik, K. AND J. Millett. CHRYSOTILE ASBESTOS IN KIDNEY CORTEX OF CHRONICALLY GAVAGED RATS. U.S. Environmental Protection Agency, Washington, D.C., EPA/600/J-83/011.

Description:

Using the transmission electron microscope, asbestos fibers have been assessed in kidney cortex of four groups of rats previously exposed to intermediate range feeding grade chrysotile asbestos. Newborn rats, from mothers gavaged with asbestos during pregnancy, were gavaged twice a week at the dose level of 50 mg/kg beginning at age day 7 until their natural death or sacrifice. Four groups of rats consisted of ages ranging from 0-200, 200-400, 400-600 and 600-800 days.

Record Details:

Record Type:DOCUMENT( REPORT )
Product Published Date:05/24/2002
Record Last Revised:04/16/2004
Record ID: 41042