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THE EFFECT OF CONTROLLED OZONE EXPOSURE ON HUMAN LUMPHOCYTE FUNCTION
Citation:
Peterson, M., R. Smialowicz, S. Harder, B. Ketcham, AND D. House. THE EFFECT OF CONTROLLED OZONE EXPOSURE ON HUMAN LUMPHOCYTE FUNCTION. U.S. Environmental Protection Agency, Washington, D.C., EPA/600/J-81/508 (NTIS PB82258880).
Description:
The effects of ozone (03) on cell-mediated immunity were studied in 16 human subjects exposed to 1176 micrograms/cu.m. 03 (0.6 ppm) for 2 hr in an environmentally controlled exposure chamber. Venous blood smaples were taken before and immediately after controlled air and 03 exposures, as well as at 72 hr, 2 and 4 weeks, and at one random time at least 1 month after treatment. The relative frequency of T lymphocytes in blood and the in vitro blastogenic response of lymphocytes to phytohemagglutinin (PHA), concanavalin A (Con A), pokeweed mitogen (PWM), and Candida albicans were determined.