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EVOKED POTENTIALS, PHYSIOLOGICAL METHODS WITH HUMAN APPLICATIONS
Citation:
Dyer, R. EVOKED POTENTIALS, PHYSIOLOGICAL METHODS WITH HUMAN APPLICATIONS. U.S. Environmental Protection Agency, Washington, D.C., EPA/600/D-89/063 (NTIS PB89223614).
Description:
A number of tests and test batteries have been developed and implemented for detecting potential neurotoxicity in humans. n some cases test results may suggest specific dysfunction. hile tests in laboratory animals are often used to project the potential for adverse health effects in humans, reverse extrapolation may also be desirable. hen changes in physiological measures are indicated in humans, it may be important to pinpoint the nature of the effect, and to understand its underlying biology. irst step in this process can be taken using animal models with demonstrated homology to the human case. his paper will focus upon 3 physiological methods which have been used in the neurological clinic to evaluate sensory function in humans, and which have also been used in laboratory animals to evaluate toxicant-induced dysfunction.