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OLFACTORY EVOKED RESPONSES TO ODOROUS STIMULI OF DIFFERENT INTENSITIES
Citation:
Prah, J. AND V. Benignus. OLFACTORY EVOKED RESPONSES TO ODOROUS STIMULI OF DIFFERENT INTENSITIES. U.S. Environmental Protection Agency, Washington, D.C., EPA/600/J-92/432 (NTIS PB93141315).
Description:
In comparison to other senses the electrophysiology of olfaction has been little studied in man and some of the basic paradigms used in the study of the other senses have not yet been widely applied to its study. asic information such as the effect of stimuli of different intensitites on the olfactory evoked potential has yeat to be presented. o this end, 12 subjects received olfactometrically delivered odorant pulses of toluene at three intensity levels - 1,600, 8,000, and 16,000 ppm. ata were obtained from three electrode sites, Fz, Cz, and Pz. n ANOVA revealed significant stimulus intensity and site effects. here was no sifference in amplitude at the lowest intensitites but there was a significant increase in amplitude evoked by the 16,000 ppm stimulus. he amplitudes recorded from Fz differed from those recorded from Pz. o latency differences were found, although there was a trend toward briefer latency with greater stimulus concentration. he OEP responds in other sensory modalities. timulus control over the OEP amplitude can be obtained by varying the stimulus intensity. hese data are evidence that the common principles of sensory processing can be extended to include the sense of smell.