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EVALUATION OF THE POTENTIAL CARCINOGENICITY OF ETHYL CARBAMATE (URETHANE)
Citation:
EVALUATION OF THE POTENTIAL CARCINOGENICITY OF ETHYL CARBAMATE (URETHANE). U.S. Environmental Protection Agency, Washington, D.C., EPA/600/8-91/128.
Description:
Ethyl carbamate is a probable human carcinogen, classified as weight-of-evidence Group B2 under the EPA Guidelines for Carcinogen Risk Assessment (U.S. EPA, 1986a). Evidence on potential carcinogenicity from animal studies is "Sufficient," and the evidence from human studies is "No Data." he potency factor (F) for ethyl carbamate is estimated to be 0.64 (mg/kg/day)-1, placing R in potency group 3 according to the CAG's methodology for evaluating potential carcinogens (U.S. EPA, 1986b). Combining the weight-of-evidence group and the potency group, ethyl carbamate is assigned a "LOW" hazard ranking for the purposes of RQ adjustment.