You are here:
CHRONIC EFFECTS OF DIETARY EXPOSURE TO AMOSITE AND CHRYSOTILE ASBESTOS IN SYRIAN GOLDEN HAMSTERS
Citation:
McConnell, E., A. Shefner, J. Rust, AND J. Moore. CHRONIC EFFECTS OF DIETARY EXPOSURE TO AMOSITE AND CHRYSOTILE ASBESTOS IN SYRIAN GOLDEN HAMSTERS. U.S. Environmental Protection Agency, Washington, D.C., EPA/600/J-83/259.
Description:
Bioassays of amosite, short range (SR), intermediate range (IR) or intermediate range chrysotile asbestos in combination with the intestinal carcinogen 1,2-dimethylhydrazine dihydrochloride (DMH) were conducted with male and female Syrian golden hamsters. Amosite and both forms of chrysotile asbestos were administered at a concentration of 1% in pelleted diet for the entire lifetime of the hamster starting with mothers of the test animals. Group sizes varied from 125 to 254. There was no adverse effect on body weight gain or survival by either type of asbestos or by IR chrysotile asbestos in combination with DHM.