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BIOCHEMICAL EFFECTS OF SULFURIC ACID MIST INHALATION BY HUMAN SUBJECTS WHILE AT REST
Citation:
Chaney, S., W. Blomquist, K. Muller, AND P. DeWitt. BIOCHEMICAL EFFECTS OF SULFURIC ACID MIST INHALATION BY HUMAN SUBJECTS WHILE AT REST. U.S. Environmental Protection Agency, Washington, D.C., EPA/600/J-80/452 (NTIS PB85166775).
Description:
The study evaluated the effect of sulfuric acid aerosol exposure for 2 consecutive days on seven human biochemical blood parameters. A total of 20 human subjects were exposed to 100 micrograms per cu. m. sulfuric acid aerosol for 4 hr/day for 2 consecutive days. A total of 17 human subjects were exposed to 4 hr of ambient air on both exposure days. The chemical blood parameters were measured pre- and post-exposure, and 20 hr after the second exposure: serum glutathione, red blood cell glutathione reductase, red blood cell glucose-6-phosphate dehydrogenase, lysozyme, serum glutamic oxaloacetic acid transaminase, serum vitamin E, and 2,3-diphosphoglycerate. The results indicate no significant response in any of the seven biochemical blood parameters measured. At this level, repeated exposure did not over-burden the upper airway defense against acid aerosol.