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CHARACTERISTICS OF THE USEPA'S OFFICE OF PESTICIDE PROGRAMS' TOXICITY INFORMATION DATA BASES
Citation:
Dearfield, K.L., J. Quest, R. Whiting, H. Stack, AND M. Waters. CHARACTERISTICS OF THE USEPA'S OFFICE OF PESTICIDE PROGRAMS' TOXICITY INFORMATION DATA BASES. U.S. Environmental Protection Agency, Washington, D.C., EPA/600/J-92/191.
Description:
The United States Environmental Protection Agency's (USEPA's) Office of Pesticide Programs (OPP) requires that data from toxicity testing be submitted to the OPP to support the registration of pesticide chemicals. nce these data are submitted, they are entered into various toxicity data bases. he studies themselves are cataloged in an archival data base to allow retrieval of the study for review. eviews of toxicity studies are then placed into a separate data base which can be retrieved to support a regulatory position. oxicity information for health effects other than cancer and gene mutations from chronic exposure is reviewed through a reference dose (RfD) approach and these decisions and supporting data are entered into an RfD data base. arcinogenicity data are reviewed by a Peer Review Process and these decisions will be entered into a newly developed data base to show the regulatory decision with supporting data. he mutagenicity data are reviewed and acceptable data are entered into the Genetic Activity Profile system to catalog and display the submitted information. hese data bases contain the information used for hazard evaluations as part of the OPP review of pesticide chemicals.