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EVALUATION OF SENSORY SYSTEM FUNCTION USING REFLEX MODIFICATION OF THE STARTLE RESPONSE
Citation:
Croft, K. AND L. Sheets. EVALUATION OF SENSORY SYSTEM FUNCTION USING REFLEX MODIFICATION OF THE STARTLE RESPONSE. U.S. Environmental Protection Agency, Washington, D.C., EPA/600/J-89/445 (NTIS PB91109371).
Description:
Methods to measure damage to sensory systems following toxicant exposure vary from rapid and subjective tests (e.g., pinna reflex) to time-consuming and objective tests (e.g., psychophysical tests). eflex modification of the startle response represents an alternative technique in the assessment of sensory function. dvantages of this procedure include: o prior training requirements, rapid and objective measurement of sensory thresholds, ability to differentiate sensory from non-sensory damage, and potential for predictive validity. his procedure has also been shown to be sensitive to a variety of neurotoxic compounds. uture research should concentrate on demonstrating the research potential of this technique for use in neurotoxicology.