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ASBESTOS AND GASTRO-INTESTINAL CANCER: CELL CULTURE STUDIES
Citation:
Reiss, B., J. Weisburger, AND G. Williams. ASBESTOS AND GASTRO-INTESTINAL CANCER: CELL CULTURE STUDIES. U.S. Environmental Protection Agency, Washington, D.C., EPA/600/1-79/023.
Description:
Three forms of asbestos: amosite, crocidolite, and chrysotile, were assayed for their cytotoxicity and mutagenicity in cell clture. Using embjryonic human intestine derived and adult rat liver derived epitelial cells, the order of toxicity was chrysotile > amosite = crocidolite. Leaching in acid slightly increased the toxicity of amosite and crocidolite and greatly decreased the toxicity of chrysotile. High concentrations of all three asbestos forms were not mutagenic in cultures of rat liver-derived epithelial cells.
Record Details:
Record Type:DOCUMENT( REPORT )
Product Published Date:05/24/2002
Record Last Revised:04/16/2004
Record ID:
34931