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Long-Term in Situ Reduction in Soil Lead Bioavailability Measured in a Mouse Model
Citation:
Bradham, K., G. Diamond, C. Nelson, M. Noerpel, K. Scheckel, B. Elek, R. Chaney, Q. Ma, AND D. Thomas. Long-Term in Situ Reduction in Soil Lead Bioavailability Measured in a Mouse Model. ENVIRONMENTAL SCIENCE & TECHNOLOGY. American Chemical Society, Washington, DC, 52(23):13908–13913, (2018). https://doi.org/10.1021/acs.est.8b04684
Impact/Purpose:
Contaminated site remedial currently involves soil removal and replacement with clean topsoil, which is expensive and difficult at contaminated sites. In situ solidification and stabilization of metals in soil may be useful for reducing human health risks associated with continued presence of contaminants.
Description:
Effects of different treatments on the bioavailability of lead (Pb) in soil from a smelter emission contaminated site in Joplin, Missouri, were evaluated in a mouse model. Similar estimates of relative bioavailability for Pb in untreated or treated soil were obtained in mice and in the well-established juvenile swine model. In the mouse model, treatments that used phosphate (phosphoric acid or triple superphosphate) combined with iron oxide or biosolids compost significantly reduced soil Pb bioavailability. Notably, effects of these remediation procedures were persistent, given that up to 16 years had elapsed between soil treatment and sample collection. Remediation of soils was associated with changes in Pb species present in soil. Differences in Pb species in ingested soil and in feces from treated mice indicated that changes in Pb speciation occurred during transit through the gastrointestinal tract. Use of the mouse model facilitates evaluation of remediation procedures and allows monitoring of the performance of procedures under laboratory and field conditions.
URLs/Downloads:
DOI: Long-Term in Situ Reduction in Soil Lead Bioavailability Measured in a Mouse Model