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GENE EXPRESSION IN PRE-IMPLANTATION MAMMALIAN EMBRYOS
Citation:
Schultz, G. AND S. Heyner. GENE EXPRESSION IN PRE-IMPLANTATION MAMMALIAN EMBRYOS. U.S. Environmental Protection Agency, Washington, D.C., EPA/600/J-93/171.
Description:
The pre-implantation mammalian embryo is initially under the control of maternal informational macromolecules that are accumulated during oogenesis. ubsequently, the genetic program of development becomes dependent upon new transcription derived from activation of the embryonic genome. everal embryonic transcripts including those that encode growth factors, cell junction components and plasma membrane ion transporters are required for normal progression of the embryo to the blastocyst stage. he pattern of genes expressed and the overall program of development is subject to the influences of genomic imprinting as well as external influences encountered by the embryo within the maternal reproductive tract.