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SYNCHRONIZATION OF RAPID GLOBIN EXPRESSION IN MURINE ERYTHROLEUKEMIC CELLS
Citation:
Zucker, R. SYNCHRONIZATION OF RAPID GLOBIN EXPRESSION IN MURINE ERYTHROLEUKEMIC CELLS. U.S. Environmental Protection Agency, Washington, D.C., EPA/600/J-85/412.
Description:
The addition of butyric acid (BA) to murine erythroleukemia cells (MELC) produces the expression of primarily A and E2 hemoglobins while DMSO incubation produces the expression of primarily A hemoglobin. Preincubation of MELC with DMSO followed by BA induction accelerates the expression of hemoglobins in a synchronous manner, yielding the preferential synthesis of alpha and y globins, and E2 hemoglobin.
Record Details:
Record Type:DOCUMENT( REPORT )
Product Published Date:05/24/2002
Record Last Revised:04/16/2004
Record ID:
33714