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Emerging Tools to Estimate and to Predict Exposures to Chemicals
Citation:
Vallero, D. Emerging Tools to Estimate and to Predict Exposures to Chemicals. Society for Risk Analysis Forum: Risk Governance for Key Enabling Technologies, Venice, ITALY, March 01 - 03, 2017.
Impact/Purpose:
Presented at the Society for Risk Analysis Forum: Risk Governance for Key Enabling Technologies, Venice, Italy, March 1-3, 2017
Description:
The timely assessment of the human and ecological risk posed by thousands of existing and emerging commercial chemicals is a critical challenge facing EPA in its mission to protect public health and the environment The US EPA has been conducting research to enhance methods used to estimate and forecast exposures for tens of thousands of chemicals. This research is aimed at both assessing risks and supporting life cycle analysis, by developing new models and tools for high throughput exposure screening and prioritization, as well as databases that support these and other tools, especially regarding consumer products. The models and data address usage, and take advantage of quantitative structural activity relationships (QSARs) for both inherent chemical properties and function (why the chemical is a product ingredient). To make them more useful and widely available, the new tools, data and models are designed to be: • Flexible • Intraoperative • Modular (useful to more than one, stand-alone application) • Open (publicly available software)
