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EVALUATION OF THE POTENTIAL CARCINOGENICITY OF N-NITROSODIETHANO-LAMINE
Citation:
EVALUATION OF THE POTENTIAL CARCINOGENICITY OF N-NITROSODIETHANO-LAMINE. U.S. Environmental Protection Agency, Washington, D.C., EPA/600/8-91/159 (NTIS PB93196434), 1988.
Description:
N-Nitrosodiethanolamine is a probable human carcinogen, classified as weight-of-evidence Group B2 under the EPA Guidelines for Carcinogen Risk Assessment (U.S. EPA, 1986a). vidence on potential carcinogenicity from animal studies is "Sufficient," and the evidence from human studies is "No Data." he results of the bioassay test used to calculate the potency factor (F) for Nnitrosodiethanolamine suggest that the experimental dose delivered to the test animals was too high (i.e., all treated animals got tumors). ence, under the CAG's methodology for evaluating potential carcinogens (U.S. EPA, 1986b), N-nitrosodiethanolamine is assigned to potency group 1. ombining the weight-of-evidence group and the potency group, N-Nitrosodiethanolamine is assigned a "HIGH" hazard ranking for the purposes of RQ adjustment.
