Science Inventory

TERATOGENIC EVALUATION AND FETAL DEPOSITION OF HEXABROMOBENZENE (HBB) AND HEXAFLUOROBENZENE (HFB) IN CD-1 MICE

Citation:

Courtney, K. AND J. Andrews. TERATOGENIC EVALUATION AND FETAL DEPOSITION OF HEXABROMOBENZENE (HBB) AND HEXAFLUOROBENZENE (HFB) IN CD-1 MICE. U.S. Environmental Protection Agency, Washington, D.C., EPA/600/J-84/013 (NTIS PB84197573), 1984.

Description:

HBB (hexabromobenzene) and HFB (hexafluorobenzene) were tested for their teratogenic potential in CD-1 mice. HBB and HFB were administered to pregnant mice from the 6th to the 16th day of gestation by gastric intubation. Neither HBB nor HFB were teratogenic or fetotoxic at doses up to 98.6 mg HBB/kg and 65.3 mg HFB/kg. No maternal toxicity was noted. HBB concentration in the fetuses indicated little, if any, accumulation. No HFB was detected in the fetal or maternal tissues 24 hours after the last dose.

Record Details:

Record Type:DOCUMENT( REPORT )
Product Published Date:12/31/1984
Record Last Revised:12/22/2005
Record ID: 31800