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BIOCHEMICAL CHANGES IN HUMANS UPON EXPOSURE TO OZONE AND EXERCISE
Citation:
Chaney, S., P. DeWitt, W. Blomquist, K. Muller, AND R. Bruce. BIOCHEMICAL CHANGES IN HUMANS UPON EXPOSURE TO OZONE AND EXERCISE. U.S. Environmental Protection Agency, Washington, D.C., EPA/600/1-79/026 (NTIS PB80105554).
Description:
A total of 44 human subjects were exposed to 784 micrograms/cu.m.(0.4 ppm) ozone and 30 human subjects were exposed to air as controls. A four hour exposure was given on each of five consecutive days. Half of each group received a higher level of treadmill exercise than the other half. Nine biochemical blood parameters were measured pre and post exposure: red blood cell glutathione reductase, vitamin E, red blood cell cholinesterase, red blood cell glucose-6-phosphate dehydrogenase, lactic acid dehydrogenase, complement C3, and IgM. Of these variables only vitamin E, red blood cell glucose-6-phosphate dehydrogenase, and complement C3 showed significant changes due to treatment.