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THE GENOTOXICITY OF INDUSTRIAL WASTES AND EFFLUENTS: A REVIEW
Citation:
Houk, V. THE GENOTOXICITY OF INDUSTRIAL WASTES AND EFFLUENTS: A REVIEW. U.S. Environmental Protection Agency, Washington, D.C., EPA/600/J-92/318 (NTIS PB92227594).
Description:
A review of the literature published on the genotoxicity of industrial wastes and effluents using short-term genetic bioassays is presented in this document. he importance of this task arises from the ubiquity of genotoxic compounds in the environment and the need to identify the sources of contamination so that efforts aimed at control and minimization can be implemented. f even greater significance is the immediate concern for the welfare of human health and the environment. subheadings of this document include an introduction, a summary of the various genetic bioassays that have been used to test industrial wastes, a compendium of methods commonly used to prepare crude waste samples for bioassay, and a review of the genetic toxicity of wastes and effluents. astes have been grouped according to major industrial source (chemical and allied products, pulp and paper manufacturing, defense and munitions, petroleum refining, and primary metal industries). ithin each industrial category, a synopsis of individual studies is presented, followed by an interpretation of results on an industry-wide basis. iscussion of the types and extent of genotoxic damage caused by a particular set of wastes is presented, and potential sources of genotoxic activity are identified. oncluding the document is a commentary that discloses potential shortcomings in the way in which current legislation protects human heath and the environment from the release of genotoxic substances via industrial wastes and effluents. t also provides an assessment of he genotoxic burden that industrial wastes place on the environment.