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Application in pesticide analysis: Liquid chromatography - A review of the state of science for biomarker discovery and identification
Citation:
Pan, P. AND J. VanEmon. Application in pesticide analysis: Liquid chromatography - A review of the state of science for biomarker discovery and identification. Chapter 18, High Performance Liquid Chromatography in Pesticide Residue Analysis. CRC Press - Taylor & Francis Group, LLC, Boca Raton, FL, 109:449-468, (2015).
Impact/Purpose:
The National Exposure Research Laboratory’s (NERL’s) Human Exposure and Atmospheric Sciences Division (HEASD) conducts research in support of EPA’s mission to protect human health and the environment. HEASD’s research program supports Goal 1 (Clean Air) and Goal 4 (Healthy People) of EPA’s strategic plan. More specifically, our division conducts research to characterize the movement of pollutants from the source to contact with humans. Our multidisciplinary research program produces Methods, Measurements, and Models to identify relationships between and characterize processes that link source emissions, environmental concentrations, human exposures, and target-tissue dose. The impact of these tools is improved regulatory programs and policies for EPA.
Description:
Book Chapter 18, titled Application in pesticide analysis: Liquid chromatography - A review of the state of science for biomarker discovery and identification, will be published in the book titled High Performance Liquid Chromatography in Pesticide Residue Analysis (Part of the Chromatographic Science Series) to be published by CRC Press Taylor & Francis Group, LLC. The chapter provides a brief summary of biomonitoring, biomarkers and their characteristics, classifications, and methods of detection. It specifically focuses on chromatographic techniques such as High Pressure (Performance) Liquid Chromatography (HPLC) with ultraviolet-visible (UV-Vis), fluorescence, refractive index, electrochemical and mass spectrometry detectors; ultra-high-pressure liquid chromatography (UHPLC) with mass spectrometry; and nano-HPLC. The book chapter highlights how sensitive and high throughput analytical methods are essential for the detection of various biomarkers of exposure to support biomonitoring studies such as the National Biomonitoring Program conducted by the Centers for Disease Control and Prevention and U.S. EPA environmental monitoring studies.
URLs/Downloads:
TABLE 18 TABLES 08-09-2013C.PDF (PDF, NA pp, 226.416 KB, about PDF)FIGURE 18 FIGURE AND FIGURE LEGEND 08-05-2013.PDF (PDF, NA pp, 543.484 KB, about PDF)
FINAL CHAPTER 18 08-05-2013 WITHOUT TABLES AND FIGURES.PDF (PDF, NA pp, 374.282 KB, about PDF)