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IRIS Toxicological Review of Tert-Butyl Alcohol (TBA) (Interagency Science Consultation Draft, 2014)
Citation:
U.S. EPA. IRIS Toxicological Review of Tert-Butyl Alcohol (TBA) (Interagency Science Consultation Draft, 2014). U.S. Environmental Protection Agency, Washington, DC, EPA/635/R-14/378, 2014.
Impact/Purpose:
EPA is undertaking a new health assessment for t-butyl alcohol (tert-butanol) for the Integrated Risk Information System (IRIS). The outcome of this project will be a Toxicological Review and IRIS and IRIS Summary of TBA that will be entered on the IRIS database. IRIS is an EPA database containing Agency scientific positions on potential adverse human health effects that may result from chronic (or lifetime) exposure to chemicals in the environment. IRIS contains chemical-specific summaries of qualitative and quantitative health information to evaluate potential public health risks associated with environmental contaminants. The IRIS database is relied on for the development of risk assessments, site-specific environmental decisions, and rule making.
Description:
On April 29, 2016, the Toxicological Review of tert-Butyl Alcohol (tert-Butanol or tBA) (Public Comment Draft) was released for public comment. The draft Toxicological Review and charge were reviewed internally by EPA and by other federal agencies and the Executive Office of the President during Step 3 (Interagency Science Consultation) before public release. As part of the IRIS process, all written interagency comments on IRIS assessments will be made publicly available. Accordingly, interagency comments with EPA's response and the interagency science consultation drafts of the IRIS Toxicological Review of tert-Butyl Alcohol and charge to external peer reviewers are posted on this site.
URLs/Downloads:
IRIS Toxicological Review of tert-Butyl Alcohol (Interagency Science Consultation Review Draft) (PDF, 142 pp, 2817 KB, about PDF)IRIS Toxicological Review of tert-Butyl Alcohol - Supplementary Information (Interagency Science Consulation Draft) (PDF, 89 pp, 1411 KB, about PDF)
Charge to Reviewers (Interagency Science Consulation Draft) (PDF, 3 pp, 126 KB, about PDF)
EPA's Response to Select Interagency Comments on the assessment for tert-Butanol (PDF, 5 pp, 177 KB, about PDF)
1. OMB/OSTP tert-Butyl Alcohol IASC Comments Nov 2014 (PDF, 1 pp, 133 KB, about PDF)
2. NTP tert-Butyl Alcohol IASC Comments Nov 2014 (PDF, 3 pp, 231 KB, about PDF)
IRIS Public Science Meeting (Dec 2013)
IRIS Public Science Meeting (Jun 2016)