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MONITORING OF THE ESTROUS CYCLE IN THE LABORATORY RODENT BY VAGINAL LAVAGE
Citation:
Cooper, R., J. Goldman, AND J. Vandenbergh. MONITORING OF THE ESTROUS CYCLE IN THE LABORATORY RODENT BY VAGINAL LAVAGE. U.S. Environmental Protection Agency, Washington, D.C., EPA/600/A-92/081.
Description:
Ovarian cyclicity in a number of laboratory species can be monitored easily and noninvasively by observing changes in the vaginal cytology. his chapter describes the techniques used to collect data in the laboratory rat and mouse and how to interpret the lavages as they are obtained. he relationship between the various cell types and the fluctuation in serum hormones as they exist over the cycle is described. inally, there is a discussion of how to interpret various changes in vaginal smear patterns as they occur in response to toxicant treatment.
Record Details:
Record Type:DOCUMENT( REPORT )
Product Published Date:05/24/2002
Record Last Revised:04/16/2004
Record ID:
30256