Science Inventory

INFLUENCE OF OZONE ON PENTOBARBITAL-INDUCED SLEEPING TIME IN MICE, RATS, AND HAMSTERS

Citation:

Graham, J., D. Menzel, F. Miller, J. Illing, AND D. Gardner. INFLUENCE OF OZONE ON PENTOBARBITAL-INDUCED SLEEPING TIME IN MICE, RATS, AND HAMSTERS. U.S. Environmental Protection Agency, Washington, D.C., EPA/600/J-81/247 (NTIS PB82249301).

Description:

Prior studies have shown that ozone (O3) increases pentobarbital (PEN)-induced sleeping time (S.T.) in female mice, rats, and hamsters. To investigate some potential mechanisms producing these effects, the authors measured zoxazolamine-induced paralysis time and thiopental- and hexobarbital-induced S.T., all of which were prolonged significantly in mice following a 5-hr exposure to 1960 micrograms O3/cu m (1 ppm).

Record Details:

Record Type:DOCUMENT( REPORT )
Product Published Date:05/24/2002
Record Last Revised:04/16/2004
Record ID: 29723