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BIODEGRADATION PROBABILITY PROGRAM (BIODEG)
Description:
The Biodegradation Probability Program (BIODEG) calculates the probability that a chemical under aerobic conditions with mixed cultures of microorganisms will biodegrade rapidly or slowly. It uses fragment constants developed using multiple linear and non-linear regressions and data from SRCs data base of evaluation biodegradation data (EFDB BIODEG file). The results have been published [Environmental Toxicology and Chemistry, volume 11, pp 593-603 (1992)]. An updated version of the program is now available that uses new expert survey data. The model uses a slight revision of the previous fragments and molecular weight to (a) calculate the probability of rapid biodegradation from the experimental data, and (b) estimate the primary and ultimate biodegradation times for complete degradation (days, weeks, months, longer) using the evaluations of 200 chemicals by 17 biodegradation experts [Environmental Science and Technology, volume 28, pp 459-465 (1994)]. The newest version of BIODEG runs under Windows 3.1 and higher (including Windows 95) making the estimation of biodegradation probability more convenient and accurate. Methods for chemical structure input now support SMILES notations as well as chemical structures produced in popular chemical drawing programs. Enhanced features of the Windows version include batch-mode data entry and user functions. BIODEG Contains 5,000 data-value records from experiments testing the biodegradable properties of more than 700 chemicals. Covers screening studies, biological treatment studies, grab sample studies, and field experiments.
