EPA Science Inventory

Use of fluorinated polybrominated diphenyl ethers and simplified cleanup for the analysis of polybrominated diphenyl ethers in house dust

Citation:

Weathers, W., M. Colon, A. Hines, AND E. Ulrich. Use of fluorinated polybrominated diphenyl ethers and simplified cleanup for the analysis of polybrominated diphenyl ethers in house dust. JOURNAL OF CHROMATOGRAPHY A. Elsevier Science Ltd, New York, NY, 1356:266-271, (2014).

Description:

A simple, cost-effective method is described for the analysis of polybrominated diphenyl ethers (PBDEs) in house dust using pressurized fluid extraction, cleanup with modified silica solid phase extraction tubes, and fluorinated internal standards. There are 14 PBDE congeners included in the method, some typically contained in the commercial mixtures used as flame retardants, and some which are not routinely reported in the peer-reviewed literature. A gas chromatographic-mass spectrometry instrumental method provides baseline separation in < 20 minutes, detection limits <20 ng/g, and quantitation limits <60 ng/g for most congeners. Method blanks contained an average concentration < 9 ng/g for all congeners except BDE209 which had an average around 40 ng/g. Spiked samples showed good accuracy with relative percent difference (RPD) <7%, and good precision with relative standard deviation <22% for all congeners except BDE209. The method was applied to the analysis of a standard dust (NIST Standard Reference Material 2585) and showed good accuracy with RPD <25% except for BDE154. Overall, this method exhibited good performance characteristics in all categories including simplicity, cost, sensitivity, selectivity, accuracy, and precision.

Purpose/Objective:

The National Exposure Research Laboratory’s (NERL’s) Human Exposure and Atmospheric Sciences Division (HEASD) conducts research in support of EPA’s mission to protect human health and the environment. HEASD’s research program supports Goal 1 (Clean Air) and Goal 4 (Healthy People) of EPA’s strategic plan. More specifically, our division conducts research to characterize the movement of pollutants from the source to contact with humans. Our multidisciplinary research program produces Methods, Measurements, and Models to identify relationships between and characterize processes that link source emissions, environmental concentrations, human exposures, and target-tissue dose. The impact of these tools is improved regulatory programs and policies for EPA.

URLs/Downloads:

Journal of Chromatography A   Exit

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Record Details:

Record Type: DOCUMENT (JOURNAL/PEER REVIEWED JOURNAL)
Start Date: 07/28/2014
Completion Date: 07/28/2014
Record Last Revised: 07/28/2014
Record Created: 07/28/2014
Record Released: 07/28/2014
OMB Category: Other
Record ID: 282258

Organization:

U.S. ENVIRONMENTAL PROTECTION AGENCY

OFFICE OF RESEARCH AND DEVELOPMENT

NATIONAL EXPOSURE RESEARCH LAB

HUMAN EXPOSURE AND ATMOSPHERIC SCIENCES DIVISION

METHODS DEVELOPMENT & APPLICATION BRANCH