EPA Science Inventory

Microwave assisted alkylation of amines with alcohols; magnetically recoverable catalysis

Citation:

Takkellapati, S. AND M. Nadagouda. Microwave assisted alkylation of amines with alcohols; magnetically recoverable catalysis. Current Organic Chemistry. Bentham Science Publishers, Ltd., Oak Park, IL, 17(20):2332-2337, (2013).

Description:

A simple, solvent free microwave assisted alkylation of amines with alcohols catalyzed by manganese oxide impregnated -Fe2O3 is reported.

Purpose/Objective:

A greener method for the alkylation of amines with alcohols using magnetic manganese oxide and microwave in the absence of any solvent is developed. This might be very useful for various alkylation reactions of amines. It is estimated that approximately 65% alkylations carried out in pharmaceutical industry are N-alkylation reactions.

URLs/Downloads:

http://www.ingentaconnect.com/content/ben/coc/2013/00000017/00000020/art00012   Exit

Record Details:

Record Type: DOCUMENT (JOURNAL/PEER REVIEWED JOURNAL)
Start Date: 10/01/2013
Completion Date: 10/01/2013
Record Last Revised: 05/30/2014
Record Created: 05/21/2014
Record Released: 05/21/2014
OMB Category: Other
Record ID: 276383

Organization:

U.S. ENVIRONMENTAL PROTECTION AGENCY

OFFICE OF RESEARCH AND DEVELOPMENT

NATIONAL RISK MANAGEMENT RESEARCH LABORATORY

SUSTAINABLE TECHNOLOGY DIVISION

CLEAN PROCESSES BRANCH