EPA Science Inventory

Toxicity and transcriptomic analysis in Hyalella azteca suggests increased exposure and susceptibility of epibenthic organisms to Zinc Oxide Nanoparticles.

Citation:

Poynton, H., J. Lazorchak, C. Impellitteri, B. Blalock, M. Smith, K. Struewing, J. Unrine, AND D. Roose. Toxicity and transcriptomic analysis in Hyalella azteca suggests increased exposure and susceptibility of epibenthic organisms to Zinc Oxide Nanoparticles. ENVIRONMENTAL SCIENCE & TECHNOLOGY. American Chemical Society, Washington, DC, 47(16):9453-9460, (2013).

Description:

Nanoparticles (NPs) are expected to make their way into the aquatic environment where sedimentation of particles will likely occur, putting benthic organisms at particular risk. Therefore, organisms such as Hyalella azteca, an epibenthic crustacean which forages at the sediment surface, is likely to have a high potential exposure. Here we show that ZnO NPs are more toxic to H. azteca compared with the corresponding metal ion, Zn2+. Dissolution of ZnO NPs contributes about 50% of the Zn measured in the ZnO NP suspensions, and cannot account for the toxicity of these particles to H. azteca. However, gene expression analysis is unable to distinguish between the ZnO NP exposures and ZnSO4 exposures at equitoxic concentrations. This suggests that the NPs act as carrier for Zn2+, increasing the exposure level of Zn2+ to H. azteca, and possibly other sediment dwelling organisms. Our study supports the prediction that sediment dwelling organisms maybe more susceptible to the effects of ZnO NPs and should be considered in the risk assessment of these nanomaterials.

Purpose/Objective:

This paper maybe the first to show the impact of nanoparticles on benthic invertebrates.

URLs/Downloads:

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Record Details:

Record Type: DOCUMENT (JOURNAL/PEER REVIEWED JOURNAL)
Start Date: 01/16/2014
Completion Date: 01/16/2014
Record Last Revised: 03/18/2014
Record Created: 01/16/2014
Record Released: 01/16/2014
OMB Category: Other
Record ID: 266767

Organization:

U.S. ENVIRONMENTAL PROTECTION AGENCY

OFFICE OF RESEARCH AND DEVELOPMENT

NATIONAL EXPOSURE RESEARCH LAB

ECOLOGICAL EXPOSURE RESEARCH DIVISION

MOLECULAR INDICATORS RESEARCH BRANCH