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Highly efficient one-pot three-component synthesis of naphthopyran derivatives in water catalyzed by hydroxyapatite
Citation:
Essamlali, Y., O. Amadine, H. Maati, K. Abdelouahdi, A. Fihri, M. Zahouily, R. Varma, AND A. Solhy. Highly efficient one-pot three-component synthesis of naphthopyran derivatives in water catalyzed by hydroxyapatite. ACS Sustainable Chemistry & Engineering. American Chemical Society, Washington, DC, 1(9):1154-1159, (2013).
Impact/Purpose:
sent for publication in the American Chemical Society (ACS) journal, ACS Sustainable Chemistry & Engineering.
Description:
An expeditious and efficient protocol for the synthesis of naphthopyrans has been developed that proceeds via one-pot three-component sequential reaction in water catalyzed by hydroxyapatite or sodium-modified-hydroxyapatite. The title compounds have been obtained in high yield and purity; the catalyst can be reused several times, making this procedure facile, practical, and sustainable.
