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The Effects of Sample Matrices on Immunoassays to Detect Microcystin-LR in Water
Citation:
Delacruz, A., T. Lynch, AND D. Dionysiou. The Effects of Sample Matrices on Immunoassays to Detect Microcystin-LR in Water. Journal of Environmental Protection. Scientific Research Publishing, Inc., Irvine, CA, 3(10):1275-1285, (2012).
Impact/Purpose:
This study is an evaluation of the effects of interfering substances commonly found in drinking and ambient water samples using commercially-available immunoassay kits for microcystin toxins.
Description:
Abstract: Immunoassays are widely used biochemical techniques to detect microcystins in environmental samples. The use of immunoassays for the detection of microcystins is vulnerable to matrix components and other interferents. This study is an evaluation of the effects of interfering substances commonly found in drinking and ambient water samples using commercially-available immunoassay kits for microcystin toxins. The microplate and strip test immunoassay formats were tested in the study. Results of this study may assist in the further refinement of existing assays and the development of practical antibody-based methods to clean-up samples and detect cyanotoxins in water. (see attached manuscript)
