EPA Science Inventory

Computational Modeling of Genital Tubercle Development

Citation:

LEUNG, M. C. Computational Modeling of Genital Tubercle Development. Presented at Joint CC3D/SBW User Training Workshop in Multi-Scale, Multi-Cell Tissue Modeling, Research Triangle Park, NC, July 30 - August 03, 2012.

Description:

See attached Power Point Presentation

Purpose/Objective:

How do androgen-responsive pathways influence specific cellular behaviors during genital tubercle development? What crosstalk exists with cellular responses to critical signaling pathways? What level of biological abstraction/detail is needed to stimulate key events leading to hypospadias? How can a CC3D model of GT development help advance predictive toxicology?

URLs/Downloads:

Computational Modeling of Genital Tubercle Development   (PDF,NA pp, 1021 KB,  about PDF)

Record Details:

Record Type: DOCUMENT (PRESENTATION/SLIDE)
Start Date: 08/04/2012
Completion Date: 08/04/2012
Record Last Revised: 10/11/2012
Record Created: 09/27/2012
Record Released: 09/27/2012
OMB Category: Other
Record ID: 246561

Organization:

U.S. ENVIRONMENTAL PROTECTION AGENCY

OFFICE OF RESEARCH AND DEVELOPMENT

NATIONAL CENTER FOR COMPUTATIONAL TOXICOLOGY

IMMEDIATE OFFICE