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Design and Evaluation of ExO: An Ontology for Exposure Science: Document Published in Nature Precedings: Pre-publication research and preliminary findings
Citation:
MATTINGLY, C. J., T. E. MCKONE, M. CALLAHAN, J. BLAKE, AND E. A. COHEN-HUBAL. Design and Evaluation of ExO: An Ontology for Exposure Science: Document Published in Nature Precedings: Pre-publication research and preliminary findings. Nature Publishing Group, London, Uk, 2011.
Impact/Purpose:
Develop an exposure ontology consistent with those being used in toxicology and other health sciences to support annotation of the outcome of exposure of a receptor (human or ecological) to a stressor (chemical, biological, physical, psychosocial). Initially focus development on human exposure to chemicals; Ultimately, provide domains that can be extended to encompass exposure data for the full range of receptors and stressors.
Description:
Significant progress has been made in collecting and improving access to genomic, toxicology, and health data. These information resources lack exposure data required to translate molecular insights, elucidate environmental contributions to diseases, assess human health risks at the individual and population levels.