You are here:
IRIS Toxicological Review of Tetrachloroethylene (Perchloroethylene) (Interagency Science Discussion Draft)
Citation:
U.S. EPA. IRIS Toxicological Review of Tetrachloroethylene (Perchloroethylene) (Interagency Science Discussion Draft). U.S. Environmental Protection Agency, Washington, DC, EPA/635/R-08/011D, 2011.
Impact/Purpose:
Tetrachloroethylene is a chemical solvent that is widely used for dry cleaning of fabrics, metal degreasing, and in making some consumer products and other chemicals.
Description:
EPA is releasing the draft report, Toxicological Review of Tetrachloroethylene (Perchloroethylene), that was distributed to Federal agencies and White House Offices for comment during the Science Discussion step of the IRIS Assessment Development Process. Comments received from other Federal agencies and White House Offices are provided below with external peer review panel comments.
URLs/Downloads:
IRIS Toxicological Review of Tetrachloroethylene (Interagency Science Discussion Draft) (PDF, 750 pp, 6679 KB, about PDF)IRIS Toxicological Review of Tetrachloroethylene (Interagency Science Discussion Draft) (Appendices Only) (PDF, 293 pp, 2075 KB, about PDF)
IRIS Summary for Tetrachloroethylene (Interagency Science Discussion Draft) (PDF, 28 pp, 283 KB, about PDF)
External Peer Review of the Application on Physiologically-Based Pharmacokinetic (PBPK) Modeling in the IRIS Toxicological Review for Tetrachloroethylene (PDF, 33 pp, 217 KB, about PDF)
EPA’s Response to Major Interagency Comments on the Interagency Science Discussion Draft IRIS Toxicological Review of Tetrachloroethylene (PDF, 9 pp, 91 KB, about PDF)
1. CDC ATSDR Perc IASD Comments (PDF, 2 pp, 34 KB, about PDF)
2. CDC NIOSH Perc IASD Comments (PDF, 4 pp, 42 KB, about PDF)
3. DOD Office of the Deputy Under Secretary of Defense (Installations & Environment) Perc IASD Comments - Part 1 (PDF, 11 pp, 82 KB, about PDF)
4. DOD Office of the Deputy Under Secretary of Defense (Installations & Environment) Perc IASD Comments - Part 2 (PDF, 2 pp, 19 KB, about PDF)
5. NASA Environmental Management Division (HQ) Perc IASD Comments (PDF, 1 pp, 52 KB, about PDF)
6. NIEHS National Toxicology Program Perc IASD Comments (PDF, 1 pp, 19 KB, about PDF)
7. OMB Office of Information and Regulatory Affairs Perc IASD Comments - Part 1 (PDF, 4 pp, 40 KB, about PDF)
8. OMB Office of Information and Regulatory Affairs Perc IASD Comments - Part 2 (PDF, 1 pp, 173 KB, about PDF)
9. SBA Office of Advocacy Perc IASD Comments - Part 1 (PDF, 4 pp, 72 KB, about PDF)
10. SBA Office of Advocacy Perc IASD Comments - Part 2 (PDF, 5 pp, 147 KB, about PDF)