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Release of ToxCastDB and ExpoCastDB databases
Citation:
JUDSON, R., E. A. COHEN-HUBAL, K. A. HOUCK, AND M. T. MARTIN. Release of ToxCastDB and ExpoCastDB databases. U.S. Environmental Protection Agency, Washington, DC, 2011.
Impact/Purpose:
The database users can now access 30 years worth of animal chemical toxicity studies that were previously only found in paper documents, data from rapid chemical testing, and various chemical exposure measurements through one online resource. The ability to link and compare these different types of data better informs EPA’s decisions about chemical safety.
Description:
EPA has released two databases - the Toxicity Forecaster database (ToxCastDB) and a database of chemical exposure studies (ExpoCastDB) - that scientists and the public can use to access chemical toxicity and exposure data. ToxCastDB users can search and download data from over 500 rapid chemical tests conducted on more than 300 environmental chemicals. ToxCast uses advanced scientific tools to predict the potential toxicity of chemicals and to provide a cost-effective approach to prioritizing which chemicals of the thousands in use require further testing. ToxCast is currently screening 700 additional chemicals, and the data will be available in 2012. ExpoCastDB consolidates human exposure data from studies that have collected chemical measurements from homes and child care centers. Data include the amounts of chemicals found in food, drinking water, air, dust, indoor surfaces and urine. ExpoCastDB users can obtain summary statistics of exposure data and download datasets. EPA will continue to add internal and external chemical exposure data and advanced user interface features to ExpoCastDB. The new databases link together two important pieces of chemical research - exposure and toxicity data - both of which are required when considering potential risks posed by chemicals. The databases are connected through EPA’s Aggregated Computational Toxicology Resource (ACToR), an online data warehouse that collects data on over 500,000 chemicals from over 500 public sources.
URLs/Downloads:
Release of ToxCastDB and ExpoCastDB databasesToxcastDB_ExpoCastDB (PDF, NA pp, 25 KB, about PDF)