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EPA's Reanalysis of Key Issues Related to Dioxin Toxicity and Response to NAS Comments (External Review Draft)
EPA has released a draft dioxin reanalysis report for a 120-day public review and comment period as stated in the Dioxin Science Plan and announced in an May 21, 2010 Federal Register (FR) Notice, with the extension in a June 23, 2010 FR Notice. During the review period, EPA will also announce by a separate FR, the details for a public teleconference (TBD) and a public panel meeting to be held on July 13-15, 2010. The deadline for comments have now been extended until September 20, 2010.
Update: EPA has replaced the draft report (main) on June 9th with a copy with included links to the reports citation's available as a reference from the HERO (https://epa.gov/hero) Database. A public listening session was also announced for July 9, 2010 in a June 14, 2010 FR Notice.
Citation:
U.S. EPA. EPA's Reanalysis of Key Issues Related to Dioxin Toxicity and Response to NAS Comments (External Review Draft). U.S. Environmental Protection Agency, Washington, DC, EPA/600/R-10/038A, 2010.
Impact/Purpose:
The objective of this report is to respond to the NAS coments on dose-response modeling conducted in the EPA Reassessment of the health effects associated with dioxin exposure.
Description:
EPA is releasing for external peer review and public comment an important draft document reviewing the literature on the health effects of dioxin and related compounds (also referred to as 2,3,7,8-Tetrachlorodibenzo-p-dioxin). At the request of Administrator Jackson, EPA is in the process of re-assessing the science on the effects of dioxin, a toxic chemical that is emitted by multiple sources, on the public’s health.
This draft dioxin report is EPA’s response to key comments and recommendations made by the National Academy of Sciences on the Agency’s draft dioxin reassessment. This assessment has been in progress for many years and raises health issues of broad interest to scientists and policymakers across the federal family. The Agency’s draft report includes significant new analyses on potential cancer and non-cancer human health effects that may result from exposures to dioxins and includes an oral reference dose for what is considered to be the most toxic of the dioxin-like compounds.
EPA’s Science Advisory Board (SAB) will convene an expert panel to review this draft report; the SAB held their first public meeting on July 13-15, 2010. Many stakeholders have significant interest in EPA’s dioxin assessment activities, and the release of this draft report will likely be of interest to environmental and health advocacy groups, the regulated community, states, media, and Congress. We want to stress that this report is a draft scientific document that is still subject to independent external peer review and public review. The Agency is committed to a transparent, scientifically sound process to determine how this chemical impacts Americans’ health.
URLs/Downloads:
EPA’s Reanalysis of Key Issues Related to Dioxin Toxicity and Response to NAS Comments (PDF, 1849 pp, 16729 KB, about PDF)EPA’s Reanalysis of Key Issues Related to Dioxin Toxicity and Response to NAS Comments (without Appendices) (PDF, 690 pp, 14675 KB, about PDF)
EPA’s Reanalysis of Key Issues Related to Dioxin Toxicity and Response to NAS Comments (Appendices Only) (PDF, 1159 pp, 6430 KB, about PDF)
Charge to External Reviewers (PDF, 7 pp, 104 KB, about PDF)
FR Notice: Jun 23, 2010
FR Notice: Jun 14, 2010
FR Notice: May 24, 2010 (SAB Mtg Announcement)
Press Release: May 21, 2010
FR Notice: May 21, 2010
Questions and Answers about Dioxin
EPA Dioxin Web site
Press Release: EPA Releases Draft Dioxin Report for Peer Review and Public Comment